Bio-Modeling Systems: The Mechanisms-Based Mecidicine Company
Bio-Modeling Systems: The Mechanisms-Based Mecidicine Companys

CADI™ (Computer Augmented Deductive Intelligence) Discovery - Value Generation


CADI™ state of the Art first collaborative research programs

  • A collaborative research between the SEPIA laboratory from the François Jacob Institute of biology par of CEA and Bio-Modeling Systems in the field of prion diseases led to a world’s first in vivo validation of the mechanisms of Creutzfeldt-Jakob disease pathogenesis & progression. Two Awards (2009 and 2010).
  • A collaborative research between the SEPIA laboratory from the François Jacob Institute of biology par of CEA and Bio-Modeling Systems in the field of prion diseases led to the filing of the co-owned patent WO201029131 describing a novel therapeutic strategy to treat psychiatric and neurological disorders. This patent is licensed exclusively on a worldwide basis to Theranexus, a CEA spin-off company.
  • A Colllaborative research in the field of biodefence and Multi-resistant bacterias threats has led to  Pherecydes-Pharma (2006): BMSystems’ spin-off, ( novel M.R. anti-bacterial nano-agents biotherapies), two indications:  Skin infections in Phase I/II. & osteo-articular infections.

Technology Developments (know-how, patents)

  • CADI™ Computer-Assisted Deductive Integration - Computer Augmented Deductive Intelligence, proprietary methodologies and tools.
  • CADI™ Search (data acquisition & mining).
  • CADI™ Architect (data organization & structuring).
  • CADI™ Fiber-N (integrative engine).
  • CADI™ View (model representation & visualization).
  • TAPE Patent: WO/2008/093010- December 2006.
  • AB-ACCUS patent: WO/2008/093009 - December 2006.
  • RIPh patent: PCT/FR2010/050796 – May 2009.
  • CNS copatent: WO/2010/029131 - Use of anti-connexin agents for modulating the therapeutic effect of psychotropic drugs. September, 2008

Valorisation of our collaborative research:

  • Spin-off (equity, etc,...).

  • Out-Licensing (royalties, etc,...).

  • Consortiums / J.V. (fees, royalties).

Contract Research (fees and possible royalties)

For more details download our Corporate Presentation

Bio-Modeling Systems: a leading Integrative Heuristic Systems Biology / Predictive Integrative Biology Mechanisms-Based Medicine company that delivers