Bio-Modeling Systems: The Mechanisms-Based Mecidicine Company
  • 2017: PRESS-RELEASE: Paris-New-York October 4, 2017: BMSystems, with its 14 independently validated successes to date, is selected by the Galien Foundation for the MedStartUp Award 2017 program first step during the US Galien Prize Forum in New-York.
     
  • 2017: ANNOUNCEMENT: Latest news:  Press-release from Hospices Civils de Lyon about phage therapy success with Pherecydes Pharma bacteriophages. Pherecydes-Pharma, is BMSystems’ first therapeutic spin-off.
     
  • 2017: ANNOUNCEMENT: Paris September 7, 2017: The future of Medicine: Bio-Modeling Systems invited to present at the Summer Universities of Fédération Hospitalière de France
     
  • 2017: ANNOUNCEMENT: Belgium August 26-27, 2017: BMSystems selected to meet Wallonia life Sciences Companies and is invited to the Spa-Francorchamps Formula 1 Race. Great place for top meeting!

  • 2017: ANNOUNCEMENT: Paris July 4, 2017. BMSystems was invited to present at the Conference INSEAD Alumni at BCG Paris Office: Everything you always wanted to know about Digital Health revolution “big promises” but were afraid to ask!

  • 2017: ANNOUNCEMENT: Paris January 17, 2017: BMSytems was invited at the France-India healthcare Summit to present its Computer Augmented Deductive Intelligence platform and its operational successes

  • 2017: ANNOUNCEMENT: Paris January 17, 2017: BMSytems invited to present its collaborative success story with CEA life Sciences at the 10 years anniversary of Medicen Paris Region Health cluster

  • 2017: Happy New Year: Our 8 Resolutions for 2017 to be ready for the upcoming bubble explosion! - Bonne Année: Nos 8 Résolutions pour 2017
     
  • 2016: INTERVIEW (Post LinkedIn FR avec explications): "Drug Discovery and health Big Data. The enormous Bubble will explode.” (Post LinkedIn ENG with all the explanations)  Manuel GEA, CEO of BMSystems in Biotech & Finances the leading biotech sector information letter

  • 2016: ANNOUNCEMENT: Paris October 5, 2016: BMSystems' CEO invited to present its digital-biology strategy and achievements at the inaugural session of Medicen Paris Region 10th years anniversary

  • 2016: PRESS RELEASE: Paris September 5, 2016: BMSystems selected to present CADI Discovery at the Connexion R&D conference organized by COSMETIC-VALLEY the leading Perfumery & Cosmetic cluster in France.

  • 2016: ANNOUNCEMENT August 1, 2016: BIO-MODELING SYSTEMS' novel Parkinson's therapy mentioned in a Report Covering 179 Companies. A new recognition of CADI Discovery capability to generate novel therapeutic strategies in complex human diseases of which CNS

  • 2016: Updated: Inaugural Presentation Bio-Entrepreneur 2015: The future will be digital and biology, but who will lead? Google? Watson? Alone or MDs, Physiologists, Biologists educating and mastering them combining diagnostics, therapies, connected devices and IT technologies?
Bio-Modeling Systems: The Mechanisms-Based Mecidicine Companys

CADI™ (Computer Augmented Deductive Intelligence) Discovery - Value Proposition

BMSystems' team builds heuristic non-mathematical CADI™ models to generate novel disruptive concepts from scientific, medical & health data.

BMSystems' answers to clients / partners' needs:

  • Physiological / Diseases Mechanisms understanding
    • Multi-Systems mechanisms
    • Multi-Scale mechanisms description
       
  • Targets discovery & validation.
  • Signatures of biomarkers discovery & validation.
  • Marketing strategies rational support
  • Adaptive clinical trials rational support
  • Market Access rational support
     
  • New therapeutic / diagnostic / cosmetics strategies,
    • New associations of molecules & devices
    • New associations of existing molecules
    • Molecules / Devices Mechanisms of action
       
  •  R&D / Molecules / clinical programs evaluation:
    • Next Phase GO / NO GO decision
    • Novel Clinical phases end points / processes
    • Drug (re) positioning /(re) profiling
    • Rare diseases drugs repositioning
    • Drug side effects analysis for rescue
    • Chemical entities safety issues (Allergy, PE, etc…)

BMSystems' markets: All applications linked to life sciences

  • Pharma, diagnostic, cosmetics: Red/biomedical Biotech.
  • Chemistry: White/Industrial biotech.
  • Environment: Yellow/environmental Biotech.
  • Energy:  Renewable Energy Biotech.

CADI™ Discovery Competitive advantages: Running life sciences R&D programs better, faster, cheaper and safer

  • Better-Faster: The CADI™ (Computer Assisted Deductive Integration) proprietary modeling approach invented in 2002 by Dr. François Iris,  is the first successful operational application of the "negative selection concept" in life sciences. This disruptive innovation in the field of systems biology places back the biologists in the center of the game, computational science providing the necessary tools to help them work better and faster.
  • Better: The CADI™ process, has proven since 2003 (first publication in history of a biologically validated model of a complex human disease) to be the most efficient synergic process combining organic non-linear integration (Brain intelligence ) and in-silico data processing power (collecting, structuring and manipulating data) to build validated biological interaction maps that describe biological reality better.
  • Better and safer: The CADI™ model can describe the dynamics of a pathological process and/or a pathological status vs. control and allows to switch from "symptomatic" to "causal" medicine. Because we work on mechanisms associated with specific pathways it becomes easier to predict and identify pertinent biomarkers and to propose new therapeutic strategies. At every steps of the preclinical and clinical development program, it is easy to go back to the model and rework it if necessary, making drug development better and safer.
  • Faster and cheaper: The CADI™ models belong to the non-mathematical holistic and heuristic class of models. Because we do not need to describe the complete system, the development of a CADI™ model leads to directly exploitable results, when the majority of our competitors are still trying to build operational systems. CADI™ is faster and cheaper.
  • Faster and cheaper: The CADI™ models are surely not exact maps of the complex reality, but they are pertinent representations that gather the minimum knowledge and intelligence necessary to describe a living process in a defined context and allows researchers to take the best possible decisions for the best possible results. They can be the most efficient necessary step to define the contexts and the parameters needed to build, local pertinent mathematical models for faster and cheaper optimization.
  • Better, faster and cheaper: The CADI™ process re-invented and made highly productive the synergic collaboration between experimental and integrative biology, implementing the unique CADI™ 4 steps validation process. Because a CADI™ model explains what, where, when to validate, it becomes possible to invent simple but highly pertinent & cost effective experimentations to get Yes/No answers better, faster and cheaper.
Bio-Modeling Systems: a leading Integrative Heuristic Systems Biology / Predictive Integrative Biology Mechanisms-Based Medicine company that delivers