Bio-Modeling Systems: The Mechanisms-Based Mecidicine Company
  • 2017: PRESS-RELEASE: Paris-November 16, 2017:BMSystems is selected to pitch at the “Translational Neurosciences Conference” organized by “NeurATRIS” and supported by “eartis” the European Infrastructure For Translational Medicine, comprising more than 80 leading European Institutes.

  • 2017: PRESS-RELEASE: Paris-New-York October 4, 2017: BMSystems, with its 14 independently validated successes to date, is selected by the Galien Foundation for the MedStartUp Award 2017 program first step during the US Galien Prize Forum in New-York.
     
  • 2017: ANNOUNCEMENT: Latest news:  Press-release from Hospices Civils de Lyon about phage therapy success with Pherecydes Pharma bacteriophages. Pherecydes-Pharma, is BMSystems’ first therapeutic spin-off.
     
  • 2017: ANNOUNCEMENT: Paris September 7, 2017: The future of Medicine: Bio-Modeling Systems invited to present at the Summer Universities of Fédération Hospitalière de France
     
  • 2017: ANNOUNCEMENT: Belgium August 26-27, 2017: BMSystems selected to meet Wallonia life Sciences Companies and is invited to the Spa-Francorchamps Formula 1 Race. Great place for top meeting!

  • 2017: ANNOUNCEMENT: Paris July 4, 2017. BMSystems was invited to present at the Conference INSEAD Alumni at BCG Paris Office: Everything you always wanted to know about Digital Health revolution “big promises” but were afraid to ask!

  • 2017: ANNOUNCEMENT: Paris January 17, 2017: BMSytems was invited at the France-India healthcare Summit to present its Computer Augmented Deductive Intelligence platform and its operational successes

  • 2017: ANNOUNCEMENT: Paris January 17, 2017: BMSytems invited to present its collaborative success story with CEA life Sciences at the 10 years anniversary of Medicen Paris Region Health cluster

  • 2017: Happy New Year: Our 8 Resolutions for 2017 to be ready for the upcoming bubble explosion! - Bonne Année: Nos 8 Résolutions pour 2017
     
  • 2016: INTERVIEW (Post LinkedIn FR avec explications): "Drug Discovery and health Big Data. The enormous Bubble will explode.” (Post LinkedIn ENG with all the explanations)  Manuel GEA, CEO of BMSystems in Biotech & Finances the leading biotech sector information letter

  • 2016: ANNOUNCEMENT: Paris October 5, 2016: BMSystems' CEO invited to present its digital-biology strategy and achievements at the inaugural session of Medicen Paris Region 10th years anniversary

  • 2016: PRESS RELEASE: Paris September 5, 2016: BMSystems selected to present CADI Discovery at the Connexion R&D conference organized by COSMETIC-VALLEY the leading Perfumery & Cosmetic cluster in France.

  • 2016: ANNOUNCEMENT August 1, 2016: BIO-MODELING SYSTEMS' novel Parkinson's therapy mentioned in a Report Covering 179 Companies. A new recognition of CADI Discovery capability to generate novel therapeutic strategies in complex human diseases of which CNS

  • 2016: Updated: Inaugural Presentation Bio-Entrepreneur 2015: The future will be digital and biology, but who will lead? Google? Watson? Alone or MDs, Physiologists, Biologists educating and mastering them combining diagnostics, therapies, connected devices and IT technologies?
Bio-Modeling Systems: The Mechanisms-Based Mecidicine Companys

CADI™ (Computer Augmented Deductive Intelligence) Discovery - Publications

CADI™ Models publications in prestigious international peer-reviewed journals

  • 2014:CNS Psychiatry publication: American Journal of Psychiatry and Neuroscience. Second publications with Max Planck  Institute of Psychiatry in Munich: Differential proteomics analyses reveal anxiety-associated molecular and cellular mechanisms in cingulate cortex. The first output of the DECIUS CNS research program. synapses.
  • 2012: CNS Neurodegenerative & Psychiatry publication: PharmacoPsychiatry publishes the first review describing a productive vision of Systems Medicine that will change R&D organization and interactions between clinicians & researchers & reveals how the world's first explanation of the mechanisms of the Creutzfeldt-Jakob disease led to the discovery of a  new therapeutic strategies for psychiatric disorders! Clearly, the brain cannot be reduced to its neurons only!
  • 2011: CNS PSYCHIATRY: Pharmaco Psychiatry publication: Fith publication with The max Planck Institute of Psychiatry in Munich: Proteome-Based Pathway Modelling of Psychiatric Disorders that describes a new analytical paradigm to definitively move research from plethoric statistical biomarkers.
  • 2010: INFECTIOUS DISEASES: Biosecurity and Bioterrorism: Biodefense Strategy, Practice, and Science Fourth publication with Pherecydes-Pharma :Genetically Engineered Virulent Phage Banks in the Detection and Control of Emergent Pathogenic Bacteria.
  • 2009. TISSUE DIFFERENTIATION : Medecine & Sciences (French) : Third CADI model validated. Mullerian regression explanation. Modelisation integrative predictive et biologie experimentale. Un processus synergique remarquablement efficace au service de la recherche medicale
  • 2005, CANCER: Journal of molecular Endocrinology: Integrative analysis of gene expression patterns predicts specific modulations of defined cell functions by estrogen and Tamoxifen in MCF7 breast cancer cells. Publication in collaboration with the INSERM unit 553.
  • 2003, CANCER: Nucleic Acids Research: Integrated transcriptome analysis of the cellular mechanisms associated with Ha-ras-dependent malignant transformation of the human breast epithelial MCF7 cell line Publication in collaboration with the INSERM unit 553. World first. First in-silico model of a complex human disease validated in-vitro and published.

Collaboration to Scientific reference books and reports

  • 2015: Publication: Cosmetics skincare: Alternative to Animal Testing : Harnessing system-level modeling to effectively alleviate the needs for animal testing.Cosmetics
  • 2014, Cosmetics skincare: Computational Biophysics of the Skin reference book. Contribution to chapter: Heuristic Modeling Applied to Epidermal Homeostasis; François Iris, Manuel Gea, Paul-Henri Lampe, and Bernard Querleux
  • 2014, European Commission: consortium CASyM:  BMSystems selected in the Europe-wide inventory of industry involve in Systems Medicine of The Coordinating Action Systems Medicine (CASyM) funded by the FP 7. The objective was to identify areas of successful innovation and exploitation.The CASyM is a multidisciplinary European consortium that joined forces to develop an implementation strategy (road map) for Systems Medicine.
  • 2010, The European Commission "From Systems Biology to Systems Medicine" report: BMSystems' heuristic systems biology research contribution to the report. The world's first explanation of the mechanisms of the Creutzfeldt-Jakob disease led to the discovery of a truly innovative psychiatric treatment recognized as one of the three best world's practice in systems medicine
  • 2008, CNS: Biomarkers for Psychiatric Disorders. (Ref. ISBN: 978-0-387-79250-7, November 2008). Dr. Francois Iris, author of the integrative biology chapter of the Book. The editor, Christoph W. Turck, is head of the Proteomics and Biomarkers branch at the Max Planck Institute of Psychiatry and holds faculty appointments in the Department of Biochemistry at Ludwig Maximilians University Munich and the International Max Planck Research School for Molecular and Cellular Life Sciences
  • 2008, CNS: Integrative Biology in the discovery of relevant biomarkers monitoring cognitive disorders pathogenesis and progression. BioTribune Springer publisher Vol. 28, august 2008.
  • 2005, Systems Biology: Computer-Assisted Integration into Biological Pathways of Modulated Gene Expressions Patterns. In «  Bioinformatics: New Research  », Yan PV editor, Chapter IV, pp 81-100 Nova Publishers (ISBN: 1-59454-242-2 2005)
Bio-Modeling Systems: a leading Integrative Heuristic Systems Biology / Predictive Integrative Biology Mechanisms-Based Medicine company that delivers